We had an amazing time last weekend on Dante's Lower East Side Tour. First off, this is a ton of food (9 stops!). Definitely do not eat anything substantial prior to this. Second, you couldn't ask for a nicer, more personable guide in Dante. He knows everything about every spot and can skip every line to get food quick. Some tours we've been on in other cities struggle with this, but Dante's been doing this a long time and is a pro.
And oh man, the food is amazing. Loved all the stops and are still talking about everything we had. Couldn't be more highly recommended.